History of Plastic Surgery

1361 BC – Tutankhamoun (“King Tut”) becomes Pharaoh of Egypt

1193 BC– Troy is destroyed by the Greeks after a prolonged siege

1250 BC – The Exodus – The Israelites under Moses leave Egypt

1000 BC – David becomes King of Israel and makes Jerusalem his capital

600 BC – Susruta’s Samhita describes nose reconstruction with the “Indian (forehead) Method” and torn earlobe reconstruction using a cheek flap. He described stitching materials made of cotton, silk, hemp, linen or horsehair

563 BC – The Buddha (Prince Siddhartha Guatama) is born

460 BC – Hippocrates, the Father of Medicine, is born on the island of Kos, Greece

214 BC – Construction of the Great Wall of China

Memphis Plastic Surgery Dr. Aldea

30 AD – an ear replantation is done by Jesus. When Judas gave Jesus his infamous kiss, the Apostles realized the betrayal. Simon Peter drew his sword and brought it on the head of the closest enemy, who happened to be Malchus, a servant to the High Priest, severing his ear. “And Jesus answered and said, Suffer ye thus far. And he touched his ear and healed him“. (St. Luke, 22, 50-51)

30 – Crucifixion of Jesus

30 – Cleopatra commits suicide

70 – Destruction of Jerusalem and the Second Temple by the Romans

129 – Claudius Galenus (Galen), future physician of Roman emperor Marcus Aurelius and writer of over 100 medical books, is born in Pergamum, nowadays, Turkey

476 – Fall of the Roman Empire and beginning of the Middle Ages

570 – Muhammad is born in Mecca (present day Saudi arabia)

1066 – William (the Conqueror) Duke of Normandy defeats Harold II at the Battle of Hastings

1096 – First Crusade

1161 – explosives introduced for first time in warfare in China

1338 – introduction of gun powder into warfare in Europe

Memphis Plastic Surgery Dr. Eby

1492 – Christopher Columbus discovers the West Indies

1492 – Leonardo da Vinci is born

1543
– Publication by Andreas Vesalius of the first scientific Anatomy textbook – De humani corporis fabrica

1560 – the Barber surgeon Hans Schaller, reportedly performed the first mastectomy for cosmetic reasons, or first EXTREME breast reduction . The patient was a maid whose “breasts assumed such great proportions that she could not support them, neither standing up nor being sitted“.

1561 – Pierre Franco, an itinerant French surgeon, describes a harelip (cleft lip) repair

1572 – St. Bartholomew’s day mass massacre of Protestants (Huguenots) in France

1580
Gasparo Tagliacozzi of Bologna, Italy describes the Italian (inner arm) Method of Nasal reconstruction1582 – The Gregorian calendar is introduced into the Roman Catholic countries

1583 – first reported eyelid lift (Blepharoplasty) for excess skin described by Georg Bartisch

1597 – Publication by Tagliacozzi of De Curatorum chirirugia, the most important book in Plastic Surgery. In which reconstruction of the nose, ears and lips were described (This is further explained on our REAL BOARD CERTIFICATION and its meaning)

1605 – Publication of Don Quixote by Miguel de Cervantes Saavedra

1607 – The colony of Virginia is founded at Jamestown

1610 – Tea is introduced into Europe

1626 – Dutch found New Amsterdam (New York)

1628
– William Harvey, an English physician educated in Padova, Italy, publishes the first true account of the circulation of blood. His bookExercitatio anatomica de motu cordis et sanguinis in animalibus(On the Movement of the Heart and Blood in Animals), was published in Frankfurt am Main, Germany. Although he became the physician to King James I, he was ridiculed in many circles as “The Circulator”, by physicians who did not believe that blood circulated.

1646 – In his book, Opera quae exstant omnia,W. Fabry von Hilden, a German surgeon, recounts an case of nasal reconstruction in 1590 by Griffon, a surgeon in Lausanne. His patient a beautiful virgin reportedly cut off her nose to prevent herself from being raped by a band of soldiers. Her nose was successfully reconstructed using a flap of skin from her arm. Griffin learned the technique from a travelling Italian surgeon.

1674 – Description of bacteria by A. van Leeuwenhoek, a Dutchman, using one of the earliest microscopes

1739 – John Wesley founds the Methodist Church

1752 – Benjamin Franklin invents the lightning rod

1756 – Wolfgang Mozart is born

1762 – Catherine becomes Tsarina of Russia

1767 – founding of King’s College (future Columbia University) Medical School in New York – The first Medical School in the American Colonies

1770 – the use of the Hevea brasiliensis tree extract as an eraser is introduced by Joseph Priestly who names the compound rubber

1773 – Boston Tea Party

1776 – American Declaration of Independence

1785 – first lip reconstruction (cheiloplasty) is performed by Chopart. Multiple modifications and innovations followed in the next 200 years by Dieffenbach, V. Ammon, Szymanowski, Nelaton, Delpech, Ombredanne, Sedillot, Bernard, Burow, Estlander, Abbe and others

1788 – Mozart writes his most famous symphonies – No. 40 (G minor) and No. 41 (C major, Jupiter)

1789 – beginning of the French Revolution

1789 – George Washington becomes the first American President

1793 – executions of Louis XVI and Marie Antoinette in Paris

1793 – Louvre Museum in Paris is open to the public

1796
Introduction of immunization (vaccination) by Edward Jenner

1800 – the first electric battery is invented by Alessandro Volta

1803 – the Louisiana Purchase

1804 – Bonaparte crowns himself Emperor Napoleon I

1807 – Slave trade is abolished throughout the British Empire over 50 years before its abolition in the United States

1809first lower eyelid reconstruction performed by Ferdinand von Graefe. Multiple innovations followed

1814Joseph Carpue successfully resurrects the Italian Method of Nasal Reconstruction, using it to build a nose of an army officer who lost it by mercury poisoning

1815 – France prohibits slave trade

1815- Napoleon is defeated at the Battle of Waterloo

1816Cleft of soft Palate successfully repaired by Ferdinand von Graefe

1816 – Rene Laennec invents the stethoscope

1824 – Ludwig van Beethoven finishes his Ninth Symphony

1837 – Victoria becomes Queen of Britain

1839 – Charles Goodyear discovers the vulcanization process, which makes rubber elastic. It revolutionized the rubber industry (Much later, rubber gloves were introduced for use in surgery)

1840 – first report of intravascular sclerotherapy of varicose veins

1844cleft lip repair with cross flap technique is introduced by Mirault. All modern repair methods evolved from this approach.

1845
Dieffenbach reconstructs a missing middle third of the ear with an advancement flap

1845first reported surgical attempt to correct prominent ears made by Dieffenbach

1846Introduction of Ether Anesthesia. Dr. John C. Warren painlessly removes a tumor from the neck of Gilbert Abbot, a 20-year-old painter, under ether administered by Dentist/medical student William Morton
1846 – Irish potato famine is at its worst

1847 – one of the earliest cases of nerve repair is described by James Paget

1848 – Gold Rush begins in California

1848 – Publication of The Communist Manifesto by F. Engels and Karl Marx

1854 – the use of the contralateral leg in reconstruction, the cross-leg flap, is described by Hamilton

1859 – Introduction of Plaster of Paris splints by Mathijsen

1859cleft palate repair with bipedicle mucoperiosteal flaps described by von Langenbeck
1859 – the International Red Cross is founded by Swiss banker Jean H. Dunant after he witnessed the horror of the Battle of Solferino (fought between Napoleon III and Austria)

1861 – Abraham Lincoln becomes President and the American Civil War begins

1863 – Emancipation Proclamation abolishes slavery in the United States

1865Joseph Lister introduces the antiseptic treatment of wounds

1866 – invention of the clinical thermometer by Thomas C. Allbutt

Memphis Plastic Surgery Dr. Aldea

1865 – Joseph Lister introduces the antiseptic treatment of wounds

1866 – invention of the clinical thermometer by Thomas C. Allbutt

1867 – Joseph Lister publishes his experience using the antiseptic treatment of wounds and revolutionizes Surgery. (Among his patients, he performed a mastectomy on his sister, Isabella Lister, using carbolic acid as an antiseptic)

1867 – United States purchases Alaska

1869 – Introduction of small skin grafts by Jacques L. Reverdin

1869 – opening of the Suez Canal

1870 – reconstruction of a scarred lower eyelid (ectropion) with full-thickness skin graft by George Lawson

1870 – New York’s first subway line is opened to the public

1870 – Franco-Prussian War begins

1873 – introduction of the bloodless field technique in hand surgery by von Esmarch

1874 – First Impressionist painting exhibition is held in Paris by Clade Monet and his colleagues

1874 – first successful tendon repair by Koenig

1876 – the first pressure steam sterilizer (autoclave) is introduced by Charles Chamberland

1876 – Chief Sitting Bull and the Sioux kill George Custer and his men at the Battle of Little Big Horn

1880 – Mastectomy for painful large breasts is recommended by Billroth

1881 – sterilization by boiling is introduced

1882 – the Tuberculosis bacillus germ is discovered by Robert Koch

1883 – Sickness (medical) Insurance is introduced in Germany

1884 – introduction of local anesthesia by Koller followed by Halsted

1885 – French chemist Louis Pasteur gives the first inoculation against rabies

1886 – John Pemberton, an Atlanta chemist, begins selling an “esteemed Brain Tonic and Intellectual Beverage” containing cocaine, caffeine and kola nut which he called Coca-Cola. (The cocaine was removed in 1903)

1887 – the Z-plasty, an ingenious method of releasing scar contractures by the rearrangement of local tissue is described by Denonvillier

1887Nasal surgery using hidden internal incisions is pioneered by John O. Roe and others

1889 – Cecil Rhodes founds British South Africa Company

1890 – Vincent van Gogh dies

1890 – a large abdominoplasty (tummy tuck) is done by Demars and Marx

1894 – Alfred Dreyfus, falsely accused of treason, is tried and deported to Devil’s Island

Memphis Plastic Surgery Dr. Aldea

1895 –X-rays are discovered by Wilhelm Conrad von Roentgen and rapidly introduced into clinical practice

1895first surgical attempt at breast reconstruction/augmentation. After removing a large benign breast tumor, Czerny filled the resulting breast defect with a fist-sized fatty tumor (lipoma) he removed from the patient’s back. The improvement was temporary

1896 – the first muscle and skin (myocutaneous) flap– the latissimus dorsi, was described by Iginio Tansini of Pavia, Italy to reconstruct mastectomy wounds. The technique was lost.

1896 – Gugliemo Marconi patents the radio receiver

1896 – gold is discovered in Klondike Creek in the Yukon Territory of Alaska

1897 – the first technique of breast lift and breast reduction was suggested by Pousson. Many improvements soon followed by Verchere, Morestin, Lexer, Joseph and others

1897 – face masks are introduced in surgery by Johannes Mikulicz-Radecki

1898vaginal reconstruction for vaginal nonformation (agenesis) is described by Robert Abbe

1898 – Spanish-American War

1899 – Second Boer War

1901 – The painter Henri de Toulouse-Lautrec dies

1901 – Marconi makes the first transatlantic radio broadcast – the letter “s”

1902 – description of the surgical joining of blood vessels (anastomosis) by Guthrie and Carrell

1903 – further refinements in the correction of prominent ears was reported by Morestin

1903 – first electrocardiograph

1903 – first motor-powered flight made by Orville Wright at Kitty Hawk, North Carolina

1904 – the first jail sentence for the crime of speeding in an automobile is handed down in Newport, Rhode Island

1905 – development of first skin graft harvesting blade by Foderl

1905 – Rasps and rotating wheels are used to dermabrade acne scars by Kromayer

1906Erich Lexer performs one of the earliest facelift operations

1906 – the San Francisco earthquake

1907 – Bone traction screws described by Lambotte

1907 – Erich Lexer becomes the first to use a saphenous vein graft in arterial repair
1907 – the first book on Cosmetic surgery, Cosmetic Surgery:the Correction of Featural Imperfections, is published privately by Charles C. Miller
1911 – the transverse elliptic incision in abdominoplasty is described by A. Morestin
1912correction of breast sagging is described by Erich Lexer
1912 – a rib graft is used to repair a mandibular defect
1912 – bony fixation with steel pins is described by Steinmann
1912 – sinking of the British ship Titanic

1913 – introduction of mammography by Salomon in Berlin
1913 – US Congress is empowered to levy income taxes with passage of the 16th Amendment to the Constitution, creating the IRS
1914 – Beginning of World War I
1915 – discovery of sodium citrate, a blood preservative, by Richard Lewisohn makes blood banks possible

1915 – Albert Einstein publishes his General Theory of Relativity

1916 – the horrific WWI Battles of Verdun, Jutland and Somme produce never before seen injuries
1917the skin tubed flap is described separately by Filatov and then by Harold Gillies

Memphis Plastic Surgery Dr. Aldea

1917 – fat grafts from the abdomen, inner thigh and buttock was used by Bartlett to fill subcutaneous mastectomy defects
1917 – Einstein publishes his Quantum Theory of Radiation which postulated that light can be generated through stimulated rather than spontaneous emission of energy – the basis of laser physics
1917 – Russian Revolution – Vladimir Lenin and the Bolsheviks seize power in Russia
1917 – the British government issues the Balfour Declaration
1919Bourguet is first to report correction of eyelid bagginess by removal of the fat out-pouchings. He later becomes the first to publish before- and after photographs and to describe the transconjunctival approach
1920 – a continuous yet hidden facelift incision is introduced by Bettman. A modified version of this incision is still currently used
1920 – (Alcohol) Prohibition begins in the United States
1920 – American women receive the right to vote (passage of the 19th Amendment to the Constitution)
1921 – American Association of Plastic Surgeons is founded
1921 – first radio newscasts are presented (KDKA in Pittsburgh)

1922 – first clinical use of Insulin

1923 – Claude Monet completes his Water Lilies series of paintings in Giverny, France

1924 – the first mechanical device for harvesting skin grafts (dermatome) is introduced by Hagen

1924 – Joseph Stalin assumes total control of the Soviet Union

1925 – School teacher John Scopes is found guilty of teaching evolution in a Tennessee public school

1926Suzanne Noël publishes her La Chirurgie Esthetique: Son Role Sociale, describing facelift, eye lift, forehead lifting, as well as correction of burns and scars

1926 – The first malpractice suit in France involved a complication of body contouring surgery. A young fashion designer went to a well-known surgeon and asked him to make her calves thinner. Before the introduction of liposuction, fat was literally scraped from under the skin. She underwent fat scraping reduction of her calves which was complicated by a severe infection resulting in one of her legs was amputated and she sued her doctor. The judge ruled for the designer.

1927 – Hollywood surgeon Herbert Otto Bames recommends undermining of facial skin in facelift

1927 – “Talking” films debut in America with the showing of The Jazz Singer starring Al Jolson

1928Alexander Fleming discovers Penicillin

1928 – Ivan Whiteside Magill, Harold Gillies’ anesthetist at Queen’s Hospital, Sidcup, UK, published his experience with single tube endotracheal anesthesia, currently the commonest way of performing general anesthesia. Magill was responsible many development in modern anesthesia

1929 – The Wall Street Crash

1930Reduction of very large breasts with the free nipple technique is described by Herbert Otto Bames

1931Corrective Nasal Surgery is popularized by Jacques Joseph

1931 – the use of long narrow hair-bearing transposition flaps in the treatment of baldness is described by Passot

1931 – Establishment of The American Society of Plastic and Reconstructive Surgeons by Jaques Maliniac and others

1932 – introduction of the pressure plate in the treatment of fractures by Danis

1932 – introduction of sulfa drugs (antibiotics)

1933 – Hitler becomes dictator of Germany

1933 – Prohibition ends

1934 – repair of abdominal wall hernias with a leg flap (tensor fascia lata iliotibial tract) is described by Wangensteen

1934 – chin augmentation using the hump removed from a prominent nose is described by Aufricht

1934 – After gangsters, Alvin Karpis and F. Barker, undergo facial altering surgery, famous gangster John Dillinger undergoes a facelift procedure including facial mole removals to change his appearance. Despite the operation, Dillinger is found and shot by the FBI outside a movie theater two months later.

1935 –an annoyed FBI director, J. Edgar Hoover, publishes a warning to surgeons in the American Journal of Surgery after “irresponsible physicians have attempted to alter the facial appearance and finger patterns of known criminals“.

1936repair of cleft palate with the push-back technique introduced by Veau

1936 – introduction into clinical practice of heparin greatly reduces clotting of repaired blood vessels

1936 – Francisco Franco becomes dictator of Spain in a military coup

1937
establishment of The American Board of Plastic Surgery

1938 – first report of flap repair of pressure ulcers by Davis

1938 – “Crystal Night” – throughout Germany bands of Nazis destroy Jewish-owned businesses and property and marks the beginning of the Nazi Holocaust

1939 – World War II begins after the German invasion of Poland

1939 – introduction of the drum dermatome by Padgett and Hood

1939treatment of baldness with hair punch grafts is described by Okuda

1941- Florey and Chain aid in mass-production of Penicillin

1942Chin enlargement by sliding horizontal osteotomy is described by Hofer

1943 – Corning Glass Works and The Dow Chemical company join to incorporate Dow Corning Corporation to develop and produce silicon chemistry polymers needed for the war effort

1943 – surrender of German forces at Stalingrad

1944- D- Day – invasion of Normandy

1945 – Atomic bombs dropped on Hiroshima and Nagaski

1946 – the beneficial use of muscle flaps in the treatment of chronic osteomyelitis is described by Stark

1946 – Nuremberg Trials of Nazi war criminals

1947 – Palestine is partitioned by the UN into Arab and Jewish states

1947 – microwaves are discovered by Percy Spencer

1948
– Lidocaine, the most commonly currently used local anesthetic agent, is introduced

1947 – the beneficial effects of correcting traumatic tattoo injuries with dermabrasion is published

1948 – Declaration of the State of Israel

1948 – formation of North Atlantic Treaty Organization (NATO)

1949Closure of Cleft (Hare) Lip with local flaps by Le Mesurier. Many improvements soon followed

1949 – Mao Tse Tung and the communists assume control of China

1950 – start of the Korean War

1951 – description by Castanares of the specific compartments of eyelid (periorbital) fat

1952 – The Spitz-Holter hydrocephalus (silicon) implantable valve shunt which prevents retardation and skull enlargement in cases of excess brain fluid (CSF) is introduced by Dow-Corning

1952 – one of the first sex change (reassignment) operations is performed by Fogh-Anderson

1952 – Elizabeth II becomes Queen of Britain

1953 – free dermofat grafts obtained from buttock donor sites are used by Bames to augment breasts

1953 – description of the double stranded helix nature of DNA by Watson and Crick

1954
first successful kidney transplantation was done by Dr. J. Murray, a Boston Plastic surgeon. Modern transplantation begins

1954 – adjacent abdominal wall dermofat flaps are used by Longacre to augment breasts

1954 – defeat of the French by the communists in Vietnam

1955 – introduction of the Ivalon (polyvinyl alcohol) plastic sponge prosthesis in breast augmentation. These implants became extremely hard and had to be removed

1955 – first successful testing of polio vaccine by Salk

1956 – Soviet Union crushes the Hungarian uprising

1956 – US Supreme Court rules as unconstitutional racial segregation on public buses

1956 – Suez Canal dispute

1957 – first pacemaker

1957 – the Treaty of Rome establishes the European Common Market

1957 – Soviet Union launches Sputnik I, the first satellite

1959Tanzer builds missing ears (microtia) with a staged approach using an implanted carved rib framework

1959 – Polistan (derivative of polyethylene) sponges used unsuccessfully in breast augmentation

1959 – Fidel Castro becomes the leader of Cuba

1960 – description of microsurgical technique by Jacobson

1960 – first demonstration of a laser

1961 – building of the Berlin Wall

1961 – Yuri Gagarin becomes the first man in space

1960’s – Etheron (derivative of polymethane) sponges used unsuccessfully in breast augmentation

1962 – first successful above-elbow replantation of an upper extremity amputation performed by Ronald Malt in Boston

1962 – the first silicone sac breast implants are used clinically by Frank Gerow and Thomas Cronin of Houston

1962 – the Cuban Missile Crisis

1963 – use of the omentum as a flap in reconstruction of radiation wounds of the chest is described by Kiricuta

1963 – omtental flaps used in breast augmentation by Zavaleta and Marino

1963 – lasers are introduced in retinal detachment procedures in ophthalmology

1963 – President Kennedy is killed in Dallas

1964
Dow Corning markets the Cronin breast implant

1964 – First work on improving the “Turkey Gobbler” deformity of the Neck is published

1964 – the CO2 laser is built by Patel at the Bell Labs

1965 – the early inflatable breast implants are described by Arion

1965 – first American Marines arrive in Vietnam

1966
establishment of muscle flap reconstruction by Ralph Ger

1966 – introduction of Medicare

1968first replantation of a severed thumb performed by Komatsu and Tamai

1968 – Soviet Union crushes the Czechoslovakian democracy movement

1969 – introduction of hypertonic saline (Sclerodex) in sclerotherapy of varicose veins

1969 – Neil Armstrong and ‘Buzz’ Aldrin of Apollo 11 walk on the Moon

1972 – introduction of the CT scan

1973first successful flap (Groin flap) transplantation using microsurgical vascular technique performed by Taylor

1973 – first report on use of laser in Plastic surgery is published by Kaplan and Ger

1973 – the guillotine is used for the last time as a means of capital punishment in French prisons

1974 – resignation of President Nixon after the Watergate scandal

1975first successful replantation with microsurgical technique of an avulsed scalp done by Miller

1976first case utilizing tissue expansion is performed by C. Radovan. Tissue expansion techniques are now used daily in breast, scalp, ear and facial reconstruction

1976first successful replantation of the penis

1976description by Mitz and Peyronie of the SMAS tissue layer of the face and the benefits tightening it may have in prolonging the effects of facelifting

1976 – The latissimus dorsi flap (originally described in 1896) is re-described by Olivari

1976breast reconstruction with microsurgically transferred soft tissue from the buttock is introduced by Fujino

1977 – the earliest liposuction technique is published by a father and son team, Arpard and George Fischer of Rome, for correction of the “saddle bags” or “riding breeches” deformity

1977 – Modern liposuction is first being practiced by Yves-Gerard Illouz in Paris

1977 – description of the rectus abdominis flap by Drever

1977 – Breast reduction with the inferior pedicle technique is described

1977 – Signing of the Camp David peace treaty between Israel and Egypt in Washington, D.C.

1979 – the Shah is expelled from Iran and Khomeini assumes power

1979 – Sixty three Americans are taken hostage in the American Embassy in Iran

1980 – Yves-Gerard Illouz publishes his technique of liposuction for body contouring

1980popularization of myocutaneous flaps by McCraw, Mathes, Nahai and Orticochea

1982
Breast reconstruction with the TRAM flap is introduced by Hartrampf and colleagues

1984
Breast reconstruction with tissue expansion is introduced

1985 – Mikhail Gorbachov becomes Soviet leader

1985 – Fournier introduces syringe liposuction

1986repair of cleft palate with double Z-plasty is published by Furlow

1986 – chin augmentation with a sliding genioplasty using miniplate fixation

1989 – End of the Cold War and the Berlin Wall comes down

1989BOTOX approved for use in Strabismus and Blepharospasm

1990Ultrasonic-Assisted Liposuction is introduced by M. Zocchi

1992 – FDA called for a moratorium on the use of silicone gel-filled implants until new safety information could be thoroughly reviewed by the Panel.

1992 – Dow Corning withdrew from the silicone implant market

1992 – FDA lifted the moratorium on breast implants and announced its decision to allow silicone gel-filled implants on the market only under controlled clinical studies for reconstruction after mastectomy, correction of congenital deformities, or replacement for ruptured silicone gel-filled implants for augmentation. FDA denied applications for using silicone breast implants for augmentation

1999 – The American Society of Plastic and Reconstructive Surgeons simplifies its name to The American Society of Plastic Surgeons

2002
– The FDA approves BOTOX for the treatment of forehead wrinkles

12/12/2003 – FDA approves Restylane, a Swedish produced hyaluronic acid filler, for skin wrinkle filling

7/20/2004 – FDA has approved Botulinum Toxin Type A (Botox) to treat severe underarm sweating known as “primary axillary hyperhidrosis” that cannot be managed by topical agents such as prescription antiperspirants. Botox has already been approved for several other purposes.

2006 – The FDA has decided there is reasonable assurance that Allergan’s (INAMED®) and Mentor’s (MemoryGel™)silicone gel breast implants are safe and effective and has now re-approved their wide use for breast enlargement in the USA for women aged 22 or over. (You may check the exact terms at the FDA’s Breast Implants website)

6/2/2006 – FDA approved Juvederm, a hyaluronic acid filler, for skin wrinkle filling
12/22/2006 – FDA expanded the use of Radiesse, an injectable Calcium Hydroxyapatite tissue filler, for moderate to severe facial folds and wrinkles

5/2/2007 – FDA approved Perlane, a Swedish produced hyaluronic acid filler which is thicker than Restylane, for deep skin wrinkle filling

12/24/2008 – FDA approved Latisse, a drug intended to make eyelashes grow longer and thicker. (Latisse is a new formulation of Lumigan, which was used to lower eyeball pressure in treating glaucoma. A side effect of Lumigan has been the growth of longer and richer eyelashes. The active ingredient in Latisse and Lumigan is Bimatoprost).


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